Creamy Pesto Chicken Pasta

Featured in: Hearty Comfort Food

This dish brings together succulent chicken, perfectly cooked pasta, and a luscious sauce infused with fresh basil pesto, cream, and Parmesan. After tossing everything in a creamy mixture, it's topped with mozzarella and more Parmesan, turning crispy and golden as it bakes. Adding spinach gives extra nutrition and flavor. The result is a bubbling, aromatic bake that suits a cozy dinner or casual gathering. Make it your own with ingredient swaps and sides for a memorable meal everyone will love.

Updated on Sat, 18 Oct 2025 15:34:22 GMT
Golden, bubbly Creamy Pesto Chicken Pasta Bake, ready from the oven and served hot. Save
Golden, bubbly Creamy Pesto Chicken Pasta Bake, ready from the oven and served hot. | dashnosh.com

This Creamy Pesto Chicken Pasta Bake is pure weeknight comfort food bubbling with mozzarella cheese and rich pesto flavor. When cold weather hits or my family needs a cozy pick-me-up, this dish delivers hearty satisfaction and feeds everyone with minimal fuss.

I first tossed this together for a potluck when I needed something stress-free yet guaranteed delicious. Now, my friends ask for it at every gathering because it vanishes fast.

Ingredients

  • Penne or rigatoni pasta: The sturdy shape holds up in the sauce and bakes beautifully Look for bronze-cut or Italian brands for the best texture
  • Boneless skinless chicken breasts: Boneless chunks cook quickly and stay juicy Choose breasts that are plump and free of excess fat
  • Olive oil: Adds flavor and helps brown the chicken Go for extra-virgin if you can
  • Salt and black pepper: Essential for bringing out all the layers of flavor
  • Unsalted butter: Gives the sauce a rich base Use real butter for that creamy finish
  • Garlic: Adds depth and a savory kick Fresh cloves are best instead of pre-minced
  • Heavy cream: Makes the sauce luscious and silky Use heavy or double cream for proper richness
  • Whole milk: Balances out the cream so it is not too heavy Whole milk is ideal
  • Basil pesto: Brings the signature herby taste Use homemade or a good store-bought kind with lots of basil and real Parmesan
  • Grated Parmesan cheese: Gives a nutty cheesy flavor throughout Freshly grated is best for melting smoothly
  • Baby spinach (optional): Boost of greens adds nutrition Look for bright green leaves with no wilting
  • Shredded mozzarella cheese: Melts into a bubbly golden crown on top Whole-milk mozzarella gets the best stretch
  • Extra Parmesan cheese: Finishes the bake with a savory sharpness

Instructions

Preheat the Oven:
Set your oven to 200 degrees Celsius or 400 degrees Fahrenheit and lightly grease your baking dish This step makes sure nothing sticks and helps the cheese turn that gorgeous golden brown
Cook the Pasta:
Bring a large pot of salted water to a boil Add your pasta and cook it for two minutes less than the package says You want it just under al dente since it will finish baking in the sauce Drain it and set aside so it is ready to toss
Brown the Chicken:
While the pasta cooks heat olive oil in your skillet on medium-high Season your chicken well with salt and pepper Add the chicken in a single layer Let it sauté without moving for a couple of minutes then stir until all the pieces are just cooked through and have a slight golden color This keeps them juicy and flavorful Take the chicken out of the pan and set aside
Build the Creamy Pesto Sauce:
In the same pan melt the butter on medium heat Once hot add the minced garlic Stir constantly for just thirty seconds until aromatic watch closely to keep it from burning
Simmer the Cream and Milk:
Pour in the heavy cream and whole milk Use a spatula to scrape up any browned bits from the pan Bring to a gentle simmer and cook for two to three minutes until the sauce starts to thicken slightly
Add Pesto and Parmesan:
Stir in the pesto and grated Parmesan cheese Mix until the sauce is smooth and the cheese has melted fully Taste and adjust for salt and pepper as needed
Combine the Pasta Chicken and Spinach:
Pour the cooked pasta chicken and baby spinach if using into the sauce Carefully toss everything together so each piece is lovingly coated and the spinach just wilts from the heat
Assemble the Bake:
Transfer the mixture to your prepared baking dish Spread it out evenly Top with shredded mozzarella and extra Parmesan for that irresistible cheesy crust
Bake Until Golden and Bubbly:
Place the dish on the center rack and bake for twenty to twenty five minutes The top should be beautifully browned and bubbling Let it rest for five minutes before scooping out so everything keeps its shape
Scoops of Creamy Pesto Chicken Pasta Bake show cheesy topping and sauce-coated penne. Save
Scoops of Creamy Pesto Chicken Pasta Bake show cheesy topping and sauce-coated penne. | dashnosh.com

I always sneak in extra spinach whenever I make this and it simply melts into the sauce My mom used to say you could taste the sunshine in any meal with good basil pesto and I think she was right

Storage Tips

Store leftovers covered in the fridge for up to four days The baked pasta keeps its creamy texture because of the rich sauce Reheat individual portions in the microwave or return the whole dish to the oven covered with foil and bake until heated through You can freeze the entire casserole either before or after baking Wrap tightly to prevent freezer burn and defrost overnight in the fridge before reheating

Ingredient Substitutions

Substitute rotisserie chicken or leftover roast chicken to save on prep Try whole-wheat or gluten-free pasta for different dietary needs If you want a vegetarian version skip the chicken and double the spinach or use sautéed mushrooms for hearty flavor

Serving Suggestions

Serve alongside a simple green salad or roasted vegetables to balance the richness Pair with garlic bread or a crusty Italian loaf for mopping up extra sauce If you like a touch of heat sprinkle a pinch of red pepper flakes over the top before baking

Cultural Context

This dish is a mashup of classic Italian basil pesto and the American love for ultra-comforting casseroles It brings together old world flavors with the ease of a familiar bake In Italy pasta al forno often uses simple tomato sauce but here the creamy pesto twist offers something totally new It is a great way to introduce basil pesto to picky eaters because the cheese and cream make it extra approachable

Seasonal Adaptations

Swap in sun-dried tomato pesto for a summery red color Use fresh peas or asparagus chopped and stirred in with the pasta during spring months Roast cherry tomatoes on top before baking for a sweet tangy pop of flavor Choose the right pasta shape so it will hold the sauce and cheese Using good aged Parmesan is key for nutty depth Do not be afraid to pack in extra greens or herbs based on what is in season

Success Stories

Kids devour this even when packed with spinach I once made this bake for a neighbor with a new baby and she said it was the best thing she ate all week One friend uses this recipe to sneak more protein into her teenage son's diet by tossing in white beans

Freezer Meal Conversion

Assemble everything in your baking dish but stop before the final bake Wrap tightly in foil and freeze up to three months Bake straight from the freezer at a lower temperature twenty minutes longer until everything is hot and bubbly

Homemade Creamy Pesto Chicken Pasta Bake: comforting Italian-American casserole with melted mozzarella. Save
Homemade Creamy Pesto Chicken Pasta Bake: comforting Italian-American casserole with melted mozzarella. | dashnosh.com

This cozy casserole always goes fast at my house and it is the ultimate comfort food for cold nights or big celebrations. Make it once and it just might become your new favorite dinner tradition.

Kitchen Q&A

Can I use other pasta shapes?

Absolutely! Penne, rigatoni, fusilli, or ziti work well and hold sauce beautifully in this bake.

Is it possible to make this vegetarian?

Yes, omit chicken and add extra spinach or sautéed mushrooms for a meat-free option with rich flavor.

Can I prepare it ahead of time?

Prepare the bake, cover, and refrigerate up to a day ahead. Bake just before serving for best results.

How do I make the sauce creamier?

Increase cream or add more Parmesan for a richer, thicker sauce. Stir until smooth before baking.

Which wine pairs well with this dish?

A crisp white wine like Pinot Grigio or Sauvignon Blanc complements the creamy pesto flavors nicely.

Is gluten-free pasta suitable?

Yes, gluten-free pasta can be substituted. Adjust cooking time as needed for your chosen brand.

Creamy Pesto Chicken Pasta

Chicken and pasta baked in creamy pesto sauce with golden mozzarella, delivering comfort and satisfying Italian-inspired taste.

Prep Duration
20 min
Cook Duration
30 min
Complete Duration
50 min
Created by Tyler Morgan

Recipe Type Hearty Comfort Food

Skill Level Easy

Cultural Heritage Italian-American

Output 4 Portion Size

Nutritional Categories None specified

What You'll Need

Pasta & Chicken

01 10.5 ounces penne or rigatoni pasta
02 2 medium boneless, skinless chicken breasts, diced (about 10.5 ounces total)
03 1 tablespoon olive oil
04 Salt and freshly ground black pepper, to taste

Creamy Pesto Sauce

01 1 tablespoon unsalted butter
02 2 cloves garlic, minced
03 3/4 cup plus 2 tablespoons heavy cream
04 1/2 cup whole milk
05 1/2 cup basil pesto (store-bought or homemade)
06 3/4 cup grated Parmesan cheese
07 3.5 ounces baby spinach (optional, for extra nutrition)

Topping

01 1 cup shredded mozzarella cheese
02 1/4 cup grated Parmesan cheese

Method

Step 01

Prepare Baking Dish and Preheat Oven: Preheat oven to 400°F (200°C). Lightly grease a 9x13-inch baking dish.

Step 02

Cook Pasta: In a large pot of boiling salted water, cook pasta for 2 minutes less than package directions, ensuring it is just under al dente. Drain and set aside.

Step 03

Sauté Chicken: Heat olive oil in a large skillet over medium-high. Season chicken pieces with salt and pepper, then sauté until cooked through and lightly golden, about 5–6 minutes. Remove from heat.

Step 04

Make Creamy Pesto Sauce: In the same skillet, melt butter over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. Stir in heavy cream and whole milk, then bring to a gentle simmer for 2–3 minutes until slightly thickened. Mix in basil pesto and grated Parmesan, stirring until smooth and melted.

Step 05

Combine Pasta, Chicken, and Sauce: Return cooked chicken, drained pasta, and spinach (if using) to the sauce. Toss thoroughly until all ingredients are evenly coated.

Step 06

Assemble and Top: Transfer the coated mixture into the prepared baking dish. Evenly sprinkle shredded mozzarella and extra Parmesan cheese over the top.

Step 07

Bake: Bake uncovered for 20–25 minutes until cheese is golden and bubbly.

Step 08

Rest and Serve: Allow dish to rest for 5 minutes before serving.

Kitchen Tools Needed

  • Large pot
  • Large skillet
  • Baking dish (9x13 in)
  • Colander
  • Mixing spoon

Allergy Alerts

Review ingredients carefully for potential allergens and seek professional medical guidance if concerned.
  • Contains milk (dairy)
  • Contains wheat (gluten)
  • May contain tree nuts if pesto includes pine nuts; verify pesto ingredients if allergies are present.

Nutrition Details (serving size)

Numbers shown are estimates only - consult healthcare providers for specific advice.
  • Energy: 670
  • Fats: 32 g
  • Carbohydrates: 56 g
  • Proteins: 41 g